Nobel Prize-Winning Frances Arnold Now Earns 2019 Bower Award for Achievement in Science

first_img Community News 6 recommendedShareShareTweetSharePin it Chemical engineer Frances Arnold Credit: Caltech“We rely on the modern chemical industry to bring us everything from prescription drugs to paper, but making these products often involves toxic chemicals and costly, energy-hungry processes.” While enzymes—biological catalysts made of protein—have long been proposed as a potential green solution for chemical manufacturing, engineering useful enzymes has proved immensely difficult.In the early 1990s, Frances H. Arnold, the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry, found a solution in a method known as directed evolution that she developed for creating new and useful versions of enzymes. Her research revolutionized enzyme design and in 2018 she won the Nobel Prize in Chemistry.Now, Arnold has been named the winner of the 2019 Bower Award for Achievement in Science. The Bower Award is among the prestigious Franklin Institute Awards, which have honored exceptional innovators in science and technology since 1824. Arnold was honored for “pioneering the development of directed protein evolution,” a monumental step forward in the science of protein engineering that revolutionized the use of biological catalysts for research and industry.Directed evolution takes a page out of nature’s playbook. Biological enzymes evolved over billions of years through random mutations and natural selection. Arnold realized that she could do something similar by selectively “breeding” new proteins for specific traits in much the same way we have guided the evolution of livestock and crops. This allowed her to create enzymes with specific, novel chemical properties.Designing a new biological catalyst through directed evolution starts with mutation of the DNA that encodes an already existing enzyme. Thousands of mutant enzymes are created from the starting enzyme and screened for a desired trait. Those enzymes that perform well are put through the same process of mutation and selection repeatedly, each generation enhancing the enzyme’s performance. This technique is so effective that it can persuade enzymes to perform reactions not found in nature; the Arnold group has created enzymes capable of making silicon-carbon bonds, boron-silicon bonds, and high-energy carbon rings called bicyclotubanes.Arnold, who is also the director of the Donna and Benjamin M. Rosen Bioengineering Center, hopes that as directed-evolution technologies grow and advance, they will increasingly supplant more traditional chemical processes, and that the day will come when much of chemical manufacturing will be performed not by humans, but by bacteria with engineered enzymes. Pasadena’s ‘626 Day’ Aims to Celebrate City, Boost Local Economy Subscribe Home of the Week: Unique Pasadena Home Located on Madeline Drive, Pasadena People Nobel Prize-Winning Frances Arnold Now Earns 2019 Bower Award for Achievement in Science By ELISE CUTTS Published on Tuesday, February 12, 2019 | 5:08 pm Community News First Heatwave Expected Next Week Get our daily Pasadena newspaper in your email box. Free.Get all the latest Pasadena news, more than 10 fresh stories daily, 7 days a week at 7 a.m. Top of the News center_img Make a comment Pasadena Will Allow Vaccinated People to Go Without Masks in Most Settings Starting on Tuesday HerbeautyRub This All Over Your Body And He’s Guaranteed To Swoon Over YouHerbeautyHerbeautyHerbeautyThese Fashion Tips Are Making Tall Girls The Talk Of The TownHerbeautyHerbeautyHerbeautyHe Is Totally In Love With You If He Does These 7 ThingsHerbeautyHerbeautyHerbeauty10 Questions To Start Conversation Way Better Than ‘How U Doing?’HerbeautyHerbeautyHerbeautyHere Is What Scientists Say Will Happen When You Eat AvocadosHerbeautyHerbeautyHerbeautyThe Most Heartwarming Moments Between Father And DaughterHerbeautyHerbeauty More Cool Stuff EVENTS & ENTERTAINMENT | FOOD & DRINK | THE ARTS | REAL ESTATE | HOME & GARDEN | WELLNESS | SOCIAL SCENE | GETAWAYS | PARENTS & KIDS Name (required)  Mail (required) (not be published)  Website  faithfernandez More » ShareTweetShare on Google+Pin on PinterestSend with WhatsApp,Virtual Schools PasadenaHomes Solve Community/Gov/Pub SafetyCitizen Service CenterPASADENA EVENTS & ACTIVITIES CALENDARClick here for Movie Showtimes Business News Your email address will not be published. Required fields are marked *last_img read more

Business community to state their case for affordable rates

first_imgEmail Print Linkedin THE Limerick business community is urged to attend a meeting at the Strand Hotel on next Tuesday, June 28, at 6.30pm, to assist in the nationwide campaign to fight for fairer and affordable rates.Employers for Affordable Rates (E.A.R), the voluntary organisation established in April, is organising a series of regional mass meetings in response to requests from all over the country.Sign up for the weekly Limerick Post newsletter Sign Up To date, employers from six regions have begun organising local groups with the aim of creating a national organisation to lobby the Government.E.A.R has also received support from business, trade and professional bodies and is gathering tremendous support nationally.Many Limerick city centre business people have repeatedly told the Limerick Post that they are struggling to cope with rates.“It is particularly difficult at the present time- business is very quiet and people are not just spending as in the past,” said one. E.A.R objects to what they describe as an inequitable system that has made the level of rates genuinely unaffordable.Rates, which the commercial sector alone has to pay, is the only funding source for local government apart from the exchequer. Employers, they argue, want fair play and say that they don’t mind paying their fair share, but point out that rates have risen by 300% since 1980 and it is unreasonable to expect them to carry this burden since they pay taxes as well.E.A.R believe they can make a compelling case to Government that will enable them achieve fair and affordable rates. Twitter WhatsAppcenter_img Previous articleCastle plan based on Hollywood rather than authenticityNext articleCllrs. sing from same hymn sheet on Opera site admin NewsLocal NewsBusiness community to state their case for affordable ratesBy admin – June 23, 2011 587 Facebook Advertisementlast_img read more