It was a tough afternoon for most of the girl golfers at Beau Pre but 2018’s top golfer, Molly Citro, found a way to win as she lead all golfers with an 82 to win her third round of the season, Tuesday afternoon in McKinleyville.As a team McKinleyville won its fourth round of the season, shooting a collective score of 427, 23 strokes better than second place Arcata (450). McKinleyville has won every team round this season expect for one at Baywood on Sept 13., which Citro did not compete in.Ci …
As any pro football player knows, having the proper equipment is critical to ensuring safety.New Raider Antonio Brown may not have that lesson down, leading to a painful foot condition.“Pro Football Talk Live” co-host Chris Simms reports that Brown’s blistered feet are the result of improper use of a cryotherapy machine. A team source confirmed that information to NFL Network’s Ian Rapoport on Wednesday before another practice Brown missed.Apparently Brown, the dazzling wide receiver in his …
(Visited 518 times, 2 visits today)FacebookTwitterPinterestSave分享0 Ross Anderson (PhD, biochemistry) is professor of biochemistry at The Master’s University in southern California. Dr Anderson’s expertise is in the area of biochemistry and molecular biology. He has taught Biochemistry and helped to direct research projects of graduate and medical students at Baylor College of Medicine, Houston, TX. Dr. Anderson was a post-doctoral researcher Houston Neurosensory Center, and was a member of both the undergraduate and graduate faculty at Lamar University, Beaumont, TX. Dr Anderson’s research interests include structure-function studies of DNA polymerizing enzymes and the synthesis and expression of synthetic human genes in bacterial hosts. He has authored or co-authored several publications in major, peer-reviewed journals. He is a member of the American Chemical Society and Sigma Xi Research Society. Another Attempt to Leap Over an Origin-of-Life Hurdle Falls Flatby Ross Anderson, Ph.D.Well, here they go again, trying desperately to provide a glimmer of hope to those who insist that life arose by lifeless processes. Three evolutionists are proposing that you can get polypeptides to form in water without intelligent design. Their new proposal has been published in Nature.An essential part of the evolutionary hypothesis is that life allegedly arose in the ocean, in what is sometimes referred to as the “prebiotic soup.” The major problem is that, until now, no one could explain how polymers of amino acids or other biomolecules could form in the presence of water. In the cell, amino acids are polymerized by molecular machines that can deal with the loss of a molecule of water for each peptide bond formed. Outside a cell, though, if the concentration of water is high, such as in the ocean, the reverse reaction would be favored; i.e., breaking peptide bonds is greatly favored over peptide bond formation. As a consequence, several investigators have proposed other scenarios where the water problem would be avoided, but all of these scenarios are not without their own problems.Louis Pasteur, 1822-1895, proved the “law of biogenesis” – life begets life.Ideology Driving the ExperimentationIt must be borne in mind that all hypotheses as to the abiogenetic origins of life are based on the philosophical ideology that there is no Creator, or that, if there is one, he is not involved and thus had no hand in the process. Consequently, evolutionists depend on their creative imaginations to speculate as to how life may have originated from non-life. Mind you, this is in spite of experiments done long ago by Louis Pasteur and others who demonstrated that life only originates from life. Such speculations also have to propose that the laws of thermodynamics didn’t apply at the beginning.As with virtually all attempts to show that life could have arisen abiogenetically—no intelligence involved—there is a considerable amount of intelligence used to develop the scenario proposed here. What makes this proposal unique is that it examines a means whereby polymerization of amino acids can occur in the presence of water.Here are the details. The series of reactions proposed by these authors consists of three reactions, what they refer to as the “ligation cycle.” It starts with a thiolysis reaction followed by a hydrolysis reaction. The authors start with a short N-acetylated peptide with a nitrile function on the C-terminus. Hydrogen sulfide (H2S) is used to displace the nitrile group from the N-acetyled peptide and, in the presence of water, generate an aminoacylthioacid. This thioacid is then set for the third reaction, an oxidation reaction, whereby the thioacid function is replaced by a nitrile derivative of an amino acid (aminonitrile); the next amino acid is ligated onto the C-terminus of the acetylated peptide. The peptide is thus extended by one amino acid and possess a nitrile function and activated for the next round of reactions.And yet these reactions will not spontaneously occur without copious amounts of investigator interference (i.e., intelligent design by lab workers pushing results in non-natural directions). Some examples of significant investigator input are as follows:First, all polymerization reactions in the cell require that the monomers being polymerized first be activated. In the case of protein synthesis, each amino acid is activated by attachment to a tRNA [transfer RNA]. The authors postulate some molecules could have been available in the prebiotic soup, such as ferricyanide, H2S, thioacetate, and cyanoacetylene. From that assumption, the authors concluded that formation of aminonitriles (amino acids with a nitrile function in place of the α-carboxyl group, AA-CN) would be likely. However, it was known that these do not lend themselves to efficient ligation or polymerization. They figured that if they could convert the AA-CN to an aminothioacid (AA-SH) which is stable and soluble in water, polymerization/ligation efficiency might be improved. The thiolysis and the hydrolysis reactions were shown to efficiently convert an AA-CN to an AA-SH. This, in turn, could participate in efficient ligation/polymerization of the next AA-CN to the C-terminus, and at the same time activate the -CN moiety for the next series of reactions in the cycle. [Note: moiety refers to an indefinite portion or share.]Second, the authors found that they first had to modify the peptide with an acetyl group on the N-terminus for several reasons: (1) Without the acetyl group, they were not able to observe the generation of the aminoacylthioacid by the hydrolysis reaction, and thus no ligation would be observed. (2) Without an N-acetyl group on the N-terminus of the growing peptide, it would be progressively destroyed by the activating agent diketopiperazine (DKP). (3) Addition of the acetyl group to the α-amino group of the peptide helped to activate the nitrile moiety making it amenable to thiolysis by H2S.Third, the authors start with short, pre-formed acetylated-peptides of glycine (Ac-Gly1-6-CN) to which they investigated the ligation of single aminonitriles, or pre-formed tripeptides. The amino acids used were all purified L-amino acids which doesn’t reflect the prebiotic soup conditions where a racemic mixture of both D- and L-amino acids would have existed. Unfortunately, the authors didn’t appear to investigate whether there is a limit to the iterative ligations after which yield drops significantly. This is important because the average number of amino acids in proteins today is 400-450 amino acids, with many being much longer. To get around this, some speculate that the first proteins were smaller; again, this is pure speculation. If that were the case, then what would be the advantage of making larger, more complex proteins?Fourth, the authors used ferricyanide to add the nitrile moiety to the amino acids, however, both ferricyanide and H2S are highly reactive toward each other, thus they had to be added in separate, sequential steps to achieve the results reported. Of course, in the prebiotic soup these two reagents would have been mixed together, thus compromising the results reported here.Getting the Sequence RightAs one can see, there was significant investigator involvement. Even if there wasn’t, this would not prove evolution. In all proteins there is information contained within the specific amino acid sequence, and this information is contained in the nucleic acid, DNA. It’s not enough to propose a scheme that may provide some plausible means for the abiotic synthesis of peptides. The scheme must have a way of specifying the sequence. It is the specific amino acid sequence that determines the 3-D conformation and thus function of a protein. One has to be mindful that the specific amino acid sequence in these experiments is determined by the investigators— not nature.The authors believe their work can inform theories about the origin of life:Amide bond formation is one of the most important reactions in both chemistry and biology, but there is currently no chemical method of achieving α-peptide ligation in water that tolerates all of the 20 proteinogenic amino acids at the peptide ligation site. The universal genetic code establishes that the biological role of peptides predates life’s last universal common ancestor and that peptides played an essential part in the origins of life.They conclude with sheer speculation that blind nature learned how to control metabolic reactions:Controlled synthesis, which responds to environmental or internal stimuli, is an essential element of metabolic regulation, and we speculate that coupling iterative aminonitrile ligation to metabolic (redox) cycles may lead to positive cooperative feedback during the early evolution of life.As we have shown, however, the investigators used design to push reactions against natural tendencies. Nature is the opposite of “controlled synthesis.”Rescuing Something Useful for DesignersWhile this paper really does nothing to further evolution, it does have some significance for researchers who need to make short, synthetic peptides for use in their research. To date, the “enemy” is water; all synthesis reactions have to be carried out under anhydrous [dry] conditions. Additionally, the amino acids used must have various blocking groups added to functional groups to prevent their reaction. For example, lysine has two amino groups, but only one of them (the α-amino group) is involved in peptide bond formation in proteins. The other amino group (the ε-amino group) must be prevented from participating in bond formation. Thus, it must be blocked by another moiety that can be readily removed later.Proteins are specified sequences of amino acids that fold into molecular machines and catalysts. (Illustra Media, Origin).The scheme reported here can permit synthesis of peptides in the presence of water, and no added blocking groups are needed. Additionally, the reaction scheme reported here also preserves the chirality, or handedness, of the ligated amino acids. Finally, these reactions may be carried out at various temperature and pH values with good yields. Thus, this report may significantly change the way small peptides are synthesized in the lab.It would also be interesting to investigate whether the polymerization of nucleotides into nucleic acids, like DNA and RNA, can occur under the conditions reported here. As long as materialistic ideology is not pushing the conclusions beyond what the facts warrant, and as long as results are not made to imply that nature can synthesize the “building blocks of life” blindly, or claim that this is how life started without a Creator, then the paper has some useful ideas for scientists using intelligence to build molecules by design.ReferenceCanavelli et al., “Peptide ligation by chemoselective aminonitrile coupling in water,” Nature 10 July 2019. https://www.nature.com/articles/s41586-019-1371-4
31 May 2010There will be aircraft in the skies around the clock to monitor traffic movements during the 2010 Fifa World Cup, with co-ordination provided by a national command centre and information available via a 24-hour call centre and route-planning website www.findyourway.co.za.With the kick-off to Africa’s first Fifa World Cup fast approaching, South Africa’s road and rail systems are ready to move the hundreds of thousands of fans that will be travelling countrywide.The government has invested more than R40-billion to ensure that the country’s public transport infrastructure can handle the expected one-million African visitors and over 300 000 overseas fans, while leaving behind a rich transport legacy for South Africans.The interactive website www.findyourway.co.za, featuring real-time route and traffic information, has been designed to help visitors plan their trips within and between the country’s nine World Cup host cities.Real-time information will feed into the command centre to enable quick decision-making, responses to incidents and appropriate law enforcement on routes with high traffic volumes.Major routes between host cities, airports, hotels, stadiums, fan parks, public viewing areas and other places of interest will receive priority attention.Road, rail and bus routes have been massively upgraded to provide an integrated transport system. In the major centres, this includes a bus rapid transit system featuring special public transport lanes and interchange nodes for commuters to switch from one form of transport to another.The Passenger Rail Agency of South Africa has also upgraded its infrastructure, increasing mobility and accessibility for commuters during the tournament.For intercity bus operations, a fleet of commuter buses provided by established operators in the business, as well as “midi-buses” provided by taxi operators, will provide an efficient service, with fleet usage dependent on demand.The upgrades have steered South Africa towards the biggest transport infrastructure investment in its history, becoming at the same time a project of building national unity, generating hope and repositioning the country.“It is not just about sport,” Transport Minister Sbu Ndebele said recently. “It is now truly about Tran-sport.”Source: BuaNews
NEXT BLOCK ASIA 2.0 introduces GURUS AWARDS to recognize and reward industry influencers Judge Rosemarie Aquilina said Nassar’s “decision to assault was precise, calculated, manipulative, devious, despicable.”“It is my honor and privilege to sentence you. You do not deserve to walk outside a prison ever again. You have done nothing to control those urges and anywhere you walk, destruction will occur to those most vulnerable.”FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSLillard, Anthony lead Blazers over ThunderSPORTSMalditas save PH from shutoutNassar found competitive gymnastics to be a “perfect place” for his crimes because victims saw him as a “god” in the sport, a prosecutor said Wednesday, shortly before the former doctor was to be sentenced for years of molesting Olympic gymnasts and other young women.“It takes some kind of sick perversion to not only assault a child but to do so with her parent in the room,” prosecutor Angela Povilaitis said. “To do so while a lineup of eager young gymnasts waited.” Slow and steady hope for near-extinct Bangladesh tortoises Larry Nassar is brought into court Tuesday, Jan. 23, 2018, in Lansing, Mich. Nassar, 54, has admitted sexually assaulting athletes under the guise of medical treatment when he was employed by Michigan State University and USA Gymnastics, which as the sport’s national governing organization trains Olympians. He already has been sentenced to 60 years in prison for child pornography. Under a plea bargain, he faces a minimum of 25 to 40 years behind bars in the molestation case. (Matthew Dae Smith/Lansing State Journal via AP)LANSING, Mich. — The former sports doctor who admitted molesting some of the nation’s top gymnasts for years was sentenced Wednesday to 40 to 175 years in prison as the judge declared: “I just signed your death warrant.”The sentence capped a remarkable seven-day hearing in which scores of Larry Nassar’s victims were able to confront him face to face in a Michigan courtroom.ADVERTISEMENT MOST READ Sports venues to be ready in time for SEA Games PLAY LIST 00:59Sports venues to be ready in time for SEA Games01:27Filipino athletes get grand send-off ahead of SEA Games00:50Trending Articles01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City Cliff Hodge return a shot in the arm for Meralco Read Next John Lloyd Cruz a dashing guest at Vhong Navarro’s wedding 2 ‘newbie’ drug pushers fall in Lucena sting Globe Business launches leading cloud-enabled and hardware-agnostic conferencing platform in PH LATEST STORIES View comments Typhoon Kammuri accelerates, gains strength en route to PH She described the “breadth and ripple” of Nassar’s sexual abuse as “nearly infinite.”“What does it say about our society that victims of sexual abuse have to hide their pain for years when they did nothing wrong? What does it say about our society when victims do come forward … and are treated as liars until proven true?” Povilaitis said.Nassar turned to the courtroom gallery to make a brief statement, saying that the accounts of more than 150 victims had “shaken me to my core.” He said “no words” can describe how sorry he is for his crimes.“I will carry your words with me for the rest of my days” he said as many of his accusers wept.ADVERTISEMENT Kammuri turning to super typhoon less likely but possible — Pagasa Brace for potentially devastating typhoon approaching PH – NDRRMC Don’t miss out on the latest news and information.
About a month ago we looked at the possibility of OSU running back Justice Hill ending the season as atop the list of freshman rushers.Well, thanks to Clemson’s domination of Ohio State (and Buckeye redshirt freshman Mike Weber’s lowest output of the season of 24 yards), it looks like that possibility will be realized.Hill’s 1,142 yards are most among FBS freshmen. The only freshman with a chance to catch him is Alabama quarterback Jalen Hurts (891 yards), and it’s not really a chance. Hurts would need 251 yards against Clemson in the national championship game.So, since that’s not happening, I’ll go ahead and congratulate Justice for another badge of honor in an impressive (and record-setting) rookie campaign.Here are the top rushing freshmen for 2016-17.1. Justice Hill (Oklahoma State) – 1,142 yards / 5.5 yards per carry / 6 touchdowns2. Mike Weber (Ohio State) – 1,096 yards / 6 yards per carry / 9 touchdowns3. Benjamin Snell, Jr. (Kentucky) – 1,091 yards / 5.9 yards per carry / 13 touchdowns4. Damarea Crockett (Missouri) – 1,062 yards / 6.9 yards per carry / 10 touchdowns5. Trayveon Williams (Texas A&M) – 1,057 yards / 6.8 yards per carry / 8 touchdowns While you’re here, we’d like you to consider subscribing to Pistols Firing and becoming a PFB+ member. It’s a big ask from us to you, but it also comes with a load of benefits like ad-free browsing (ads stink!), access to our premium room in The Chamber and monthly giveaways.The other thing it does is help stabilize our business into the future. As it turns out, sending folks on the road to cover games and provide 24/7 Pokes coverage like the excellent article you just read costs money. Because of our subscribers, we’ve been able to improve our work and provide the best OSU news and community anywhere online. Help us keep that up.
Roma 0 AC Milan 2: Cutrone and Calabria secure superb win for Rossoneri Guy Atkinson Last updated 1 year ago 05:41 26/2/2018 Getty Images AC Milan’s fine form in Serie A continued as a superb second-half display saw off an out-of-sorts Roma. AC Milan stretched their unbeaten run in Serie A to eight games as Patrick Cutrone and Davide Calabria sealed a 2-0 win over Roma at the Stadio Olimpico.Gennaro Gattuso’s side were second best during a poor first half but came out for the second period rejuvenated and secured all three points thanks to their young stars.Their more adventurous approach bore fruit after 48 minutes when Cutrone got a delicate touch to Suso’s cross, which flashed past Alisson. Article continues below Editors’ Picks Williams case shows Solskjaer isn’t holding Man Utd’s youngsters back – he’s protecting them Goalkeeper crisis! Walker to the rescue but City sweating on Ederson injury ahead of Liverpool clash Out of his depth! Emery on borrowed time after another abysmal Arsenal display Diving, tactical fouls & the emerging war of words between Guardiola & Klopp Milan had further chances to add a second before the unlikely figure of Calabria added gloss to the scoreline with a composed finish in the 74th minute.The win sets Milan up perfectly for a big week, which sees them face Lazio in a Coppa Italia semi-final second leg on Wednesday before a crunch derby with Inter four days later.Roma, meanwhile, will need to pick themselves up quickly after a second consecutive defeat ahead of a daunting trip to Napoli next weekend.74′ AND @davidecalabria2 MAKES IT TWO!!!! Il raddoppio rossonero con un gran gol di Davide!!! Dai ragazzi!!!!! ️ #RomaMilan 0-2 pic.twitter.com/1tvqQquMrI — AC Milan (@acmilan) February 25, 2018 Roma started with a spring in their step and tested Gianluigi Donnarumma – celebrating his 19th birthday – twice inside the opening 10 minutes through Cengiz Under and Diego Perotti.Milan soon settled, however, and largely kept their hosts at arm’s length for large swathes of the first half.When Roma did threaten, Lorenzo Pellegrini was at the heart of it. The 21-year-old midfielder had a penalty appeal waved away before flashing a shot wide of Donnarumma’s right-hand post as the half ended goalless.In stark contrast to their tepid first-half display, Milan started the second period with verve and swagger and were rewarded with the opening goal after just three minutes.Cutrone found Suso on the right and then stormed into the box to meet the Spaniard’s teasing cross with an impudent flick past Alisson for his sixth Serie A goal of the season.48′ GOOOOOOOOOOOOOOOOAAAAAAAAAL! Patrick!!!!CUTRONEEEE! Vantaggio rossonero! ️ #RomaMilan 0-1 pic.twitter.com/raTN3gmnax — AC Milan (@acmilan) February 25, 2018 Perotti then drilled a long-range effort just wide as Roma attempted to restore parity, while Alisson had to be alert to parry over Franck Kessie’s powerful drive as Milan looked to double their advantage.The shackles were well and truly off Milan’s players after Cutrone’s goal and Hakan Calhanoglu should have at least tested Alisson with a low drive just before the hour, instead dragging it wide.Substitute Nikola Kalinic should have wrapped it up with 20 minutes remaining but was denied by a smart one-handed save from Alisson.The Croatian made up it for it soon after, though, playing in the marauding Calabria who coolly clipped over the onrushing Roma goalkeeper for his first ever Serie A goal.Roma rarely looked like clawing their way back into the game in the closing stages as Milan – who could have had a third late on through Fabio Borini – comfortably held firm to register a memorable win. Key Opta Facts:- AC Milan have won an away league match against Roma for the first time since October 2011.- Patrick Cutrone has scored four goals in his last four Serie A games. His strike on Sunday was Milan’s first shot on target of the match.- Davide Calabria has scored his first goal for AC Milan (42 apps in all competitions). read more
Liverpool Salah can beat De Bruyne to Premier League awards – Klopp Ryan Benson 08:00 4/3/2018 FacebookTwitterRedditcopy Comments(0) Liverpool Mohamed Salah Liverpool v Newcastle United Premier League Jürgen Klopp Kevin De Bruyne The Egyptian scored again on Saturday and the Liverpool boss expects him to challenge for individual honours at the season’s end Jurgen Klopp sees no reason why Mohamed Salah cannot beat Manchester City star Kevin De Bruyne to the end-of-season awards after another fine performance in Liverpool’s 2-0 win over Newcastle United.Salah scored the opening goal at Anfield to take his tally to 24 from 28 Premier League games in his first season since moving from Roma.He has also set up another eight goals, becoming the key figure for Klopp’s Liverpool in their rise above Manchester United into second place. Editors’ Picks Williams case shows Solskjaer isn’t holding Man Utd’s youngsters back – he’s protecting them Goalkeeper crisis! Walker to the rescue but City sweating on Ederson injury ahead of Liverpool clash Out of his depth! Emery on borrowed time after another abysmal Arsenal display Diving, tactical fouls & the emerging war of words between Guardiola & Klopp De Bruyne had seemingly made himself the big favourite for the individual accolades with his consistently impressive performances for runaway leaders City, particularly in the first half of the campaign.But Salah has emerged as a serious contender and Klopp feels he will deserve any recognition that comes his way.When asked if he thought Salah can prevail over De Bruyne, Klopp told reporters: “Of course. It’s a different position, it depends what you want.”There’s no doubt Kevin De Bruyne plays a nice season; there’s no doubt Mo Salah plays a really good one as well.”Not only him, there are a few more players. A few people would mention that Harry Kane is not too bad and Roberto Firmino is not too bad.”David Silva had a few weeks where for private reasons he couldn’t play, but he plays an outstanding season as well.Another one @22mosalah . Strong performance from the boys today and a good win! #YNWA pic.twitter.com/sB9CDyGTIL — Alex Ox-Chamberlain (@Alex_OxChambo) March 3, 2018 “There are a few good players this season in the Premier League – and for sure I forgot a few. In our team, I like a lot of what we did so far.”I don’t have to make the decision. At the end there will be one winner and a few more very good players around him.”That’s what the life of a professional sportsman is. You do it because you want to win. I don’t think a lot of people are doing this only to be part of it.”We want to win things – that’s a big part of our personality. For me, [individual] trophies mean absolutely nothing. I have no clue why it’s like that, but it is the truth.”Winning a title with a team is different, to be honest, but I respect it. If he [Salah] can win this competition then he deserves it.”There are a few games to go and we have to make sure he can keep on going in this shape, be in important spaces and very decisive areas, and score goals for us.”Liverpool return to Champions League action Tuesday with the second leg of their last-16 ties against Porto.
Transfers Transfer news & rumours LIVE: Madrid deny Lewandowski deal Goal Last updated 1 year ago 04:45 18/3/2018 FacebookTwitterRedditcopy Comments(1) Getty Images Transfers Primera División Premier League Bundesliga Serie A Ligue 1 Goal takes a look at the biggest transfer news and rumours from the Premier League, La Liga, Serie A and beyond Madrid deny Lewandowski dealReal Madrid president Florentino Perez has told Bayern Munich CEO Karl-Heinz Rummenigge that his club haven’t agreed terms with Robert Lewandowski, according to Münchner Merku. Mundo Deportivo had claimed that Madrid have settled on personal terms with Lewandowski over a deal for the Bayern striker to move to the Santiago Bernabeu in the summer.However, despite ongoing speculation that Lewandowski could leave the Allianz Arena at the end of the season, Perez has informed Rummenigge that there has been no contact. Article continues below Editors’ Picks Williams case shows Solskjaer isn’t holding Man Utd’s youngsters back – he’s protecting them Goalkeeper crisis! Walker to the rescue but City sweating on Ederson injury ahead of Liverpool clash Out of his depth! Emery on borrowed time after another abysmal Arsenal display Diving, tactical fouls & the emerging war of words between Guardiola & Klopp Courtois commits future to ChelseaThibaut Courtois has quashed talk of an imminent move to Real Madrid by vowing to spend at least one more season at Chelsea.“I have a contract until next year and I will be here. I will do my best for it.“Obviously there is no extension signed but I don’t think now is the moment to do it. I think it is better to wait until the end of the season.“All I can say is I’m committed to Chelsea and also committed for next year.”Read the full story on Goal. Man City prepare Kane & Isco swoopTottenham star Harry Kane and Real Madrid midfielder are the subject of a sensational double transfer bid from Manchester City, according to Diario Gol . The midfielder is on the outs with Los Blancos and Pep Guardiola is ready to move for him. The report claims that Kane will follow him to City, with the England forward apparently excited to play alongside the 25-year-old Spaniard and willing to snub Madrid if he is sold. Dortmund to offer €40m for MartinezBorussia Dortmund are ready to offer €40 million for Racing Club striker Lautaro Martinez, reports Fox Sports . Inter Milan had appeared to be leading the race to sign Martinez, who had reportedly agreed personal terms in principle regarding a move to Serie A.However, Dortmund have now entered the bidding and are looking to bring in the Argentine attacker after this summer’s World Cup. Bale happy at Real MadridZinedine Zidane insists Gareth Bale is happy at Real Madrid despite his limited playing time in the Champions League.Wales star Bale has battled injuries again this season, featuring only twice in the group stage, but he was fit for the double-header with Paris Saint-Germain as Zidane twice left him out of the starting line-up.However, while the former Tottenham winger is consistently the subject of reports suggesting he could return to the Premier League, his coach is confident he is content with his role at Santiago Bernabeu.Read the full story on Goal right here! Everton to offer Wilshere £8m signing-on feeEverton are ready to offer Jack Wilshere an £8 million signing-on fee to join the club on a free transfer from Arsenal, reports The Times . Wilshere is out of contract at the end of the season and has grown frustrated with how talks over a new deal have progressed .Arsenal remain optimistic of being able to agree a deal with the midfielder, but Everton are hoping to tempt the England international to Goodison Park.Can to replace Modric at MadridEmre Can has been chosen as the man to replace Luka Modric at Real Madrid this summer, El Gol Digital reports. Modric is drawing interest from a host of Premier League teams and his time with the Spanish giants is coming to a close. But Los Blancos have already decided that the Liverpool midfielder, who is out of contract this summer, will be his replacement and have moved to close a deal. Arsenal want Andre Silva from MilanArsenal are in the race to sign Milan forward Andre Silva this summer, with Wolves also looking at an audacious run at the 22-year-old should they return to the Premier League, report The Mirror .The Portuguese forward has struggled since moving to Serie A from Porto this summer, but the Gunners are still interested in the youngster, who has shown well in the Europa League. Arsenal & Liverpool to battle for OblakArsenal and Liverpool are set to face off over the signing of Atletico Madrid goalkeeper Jan Oblak, according to AS . The Reds have made their interest in the 25-year-old clear, but Arsenal have now stepped up their pursuit of the Slovenian. Oblak has a release clause of €100million, and both clubs are prepared to meet that demand.Conte downplays Champions League impactAntonio Conte played down the impact missing out on the Champions League would have on Chelsea’s pulling power in the transfer market as his side fight to finish in the Premier League’s top four.”Don’t forget that two years ago, Chelsea finished 10th with many players of this season, and they decided to continue to play for this club,” he told reporters.”I think this is not a question for me, it’s a question for the players.”Read the full story on Goal right here! City could move for GriezmannPep Guardiola could move for Antoine Griezmann this summer upsetting plans at Barcelona to bring the striker in, Diario Gol claims.While Harry Kane is said to be the top target for Manchester City, Griezmann is Guardiola’s secondary option, and the Premier League side could use Sergio Aguero as part of the deal to top any offer from Barcelona. Emery: Neymar to Madrid? Ask FlorentinoUnai Emery says Real Madrid president Florentino Perez should be asked about Neymar’s future at Paris Saint-Germain. “The PSG project is very strong with Neymar in it,” he said. “As for Real Madrid? I don’t know, ask Florentino.”Read the full story on Goal. Liverpool ready to beat Madrid to AlissonLiverpool are ready to pay £70million in an attempt to beat Real Madrid to the signing of Roma goalkeeper Alisson, Don Balon claims. A different report from the same outlet also claims that Chelsea could move for the Brazilian as a replacement for Thibaut Courtois.Man Utd & Chelsea to raid NapoliManchester United and Chelsea are looking to raid Napoli this summer, reports Forza Italian Football. Jose Mourinho wants to land midfielder Jorginho while Chelsea are hoping to land Kalidou Koulibaly. Both club also hold an interest in Dries Mertens, though there will be fierce competition for the Belgian, according to the report. Alisson: Madrid links good for my ego!Roma goalkeeper Alisson has acknowledged reports of a potential move to LaLiga heavyweights Real Madrid “massage the ego”.The Brazil international is reportedly a target for several top teams throughout Europe, with Liverpool said to be preparing a £70million bid during the close-season.Read his full comments right here on Goal Newcastle set Sels priceNewcastle have set their asking price for Matz Sels at £4.5million, Belgian outlet La DH reports.Sels is on loan at Anderlecht, and while the Belgian club would love to sign him the price could be more than they can afford.
Spurs boss Pochettino not ready to write off Janssenby Paul Vegas10 months agoSend to a friendShare the loveTottenham aren’t ready to sell Vincent Janssen just yet.The Daily Mail says Tottenham are set to hold talks with out-of-favour Janssen as they consider letting the striker leave in the January transfer window. Janssen returned from a foot injury on Monday as he played 45 minutes for Tottenham Under 23s in 1-1 draw with Liverpool.Spurs boss Mauricio Pochettino will hold talks with striker Janssen this week as the club weigh up whether to sell the Dutchman this month. And the forward could yet revive his flagging Spurs career if he can prove his worth to Pochettino this month. TagsTransfersAbout the authorPaul VegasShare the loveHave your say